CMS released an interim final rule requiring Medicaid beneficiaries ages 19-64 to complete 80 hours monthly of work or qualifying activities starting January 1, 2027. While exemptions exist for pregnant individuals, caregivers, and medically frail beneficiaries, experts warn the narrower medical frailty definition could cause coverage losses. The rule is effective July 31, 2026, with public comments accepted through that date.

Five states enacted significant healthcare legislation during spring 2026 sessions. Arizona launched AI-powered Medicaid fraud detection, while Iowa banned insurers from using AI to deny prior authorizations under HF 2635. Missouri's comprehensive HB 2372 awaits gubernatorial approval, expanding Medicaid coverage and hospital transparency requirements. Maryland's Prescription Drug Affordability Board capped Ozempic payments at Medicare rates for state plans. Connecticut's budget bill (SB 1) overhauled Certificate of Need requirements for hospitals.

The U.S. Supreme Court will decide by May 14, 2026, whether to reinstate mifepristone's in-person dispensing requirement nationwide, potentially reversing the FDA's 2023 change allowing telehealth prescriptions and mail distribution. Louisiana's lawsuit challenges this change, with courts finding the state likely has standing. Republican attorneys general from multiple states have filed cases targeting the FDA and out-of-state abortion medication providers, intensifying conflicts with Democratic states' shield laws.

Only 13 state Medicaid programs cover GLP-1 medications for weight loss as of early 2026, down from 17 states before January 1. California, New Hampshire, Pennsylvania, and South Carolina dropped coverage citing budgetary constraints. The 13 remaining states impose strict restrictions including BMI thresholds over 30, prior authorization, and step therapy requirements. CMS introduced the BALANCE demonstration program allowing states to expand coverage through negotiated pricing beginning May 2026.

Florida's Senate Committee on Health Policy voted 6-4 on January 29th to advance SB 1756, the Medical Freedom Act, which prohibits the State Health Officer from ordering vaccinations and establishes conscience protections as exemptions from school-entry vaccine requirements. The bill requires providers to obtain signed informed consent before administering vaccines to minors and awaits consideration in the Appropriations Committee.

As federal vaccine recommendations become less consistent, states are increasingly asserting independent authority over immunization policies. Several states formed regional collaboratives for vaccine guidance and procurement in late 2025, while others enacted legislation replacing federal recommendations with state-based advisories. Conversely, some states like Florida are moving to eliminate school vaccine mandates and emphasize parental choice through regulatory changes.

Fifteen governors launched a public health alliance to improve emergency preparedness and coordination across state lines, while CMS announced all 50 states applied for the $50 billion Rural Health Transformation Program. California enacted major healthcare transparency and PBM oversight legislation, Colorado proposed significant Medicaid spending cuts, and Massachusetts advanced prior authorization reforms.